Melatonin Mystery Key to A Sleepless Stress: A Cross-Sectional Study among Emergency Doctors of LUMHS, Sindh, Pakistan

Effects of Melatonin on Doctors Working in Emergency Department

  • Jehanzeb Dars Lecturer, Department of Physiology, Liaquat Institute of Medical and Health Sciences / LUMHS Thatta, Pakistan
  • Salma Farukh Memon Professor, Department of Physiology, Liaquat University of Medical & Health Sciences Jamshoro, Pakistan
  • Shakil Ahmed Shaikh Assistant Professor, Department of Physiology, Suleman Roshan Medical College Tando Adam, Pakistan
  • Abdul Waheed Buledi Senior Lecturer, Department of Physiology, Mekran Medical College, Turbat Pakistan
  • Aneeb Mengal Assistant Professor, Department of Physiology, Jelwan Medical College, Khuzdar Pakistan
  • Moomal Tagar Lecturer, Department of Physiology, Liaquat University of Medical & Health Science, Jamshoro Pakistan
Keywords: Melatonin, PTSD, Insomnia

Abstract

Objective: To find the relationship of serum melatonin with circadian rhythm disruption (insomnia) and stress-related disorder (PTSD) and to find the relationship between serum levels of melatonin with PTSD and insomnia. Study Design: Cross-sectional study. Settings: Physiology Department of LUMHS, in collaboration with clinical wards and D R (Diagnostic Research) Lab at LUMHS. Duration: August 2021 to March 2022. Methods: The participants were adult male and female doctors performing emergency duties at Liaquat University of Medical & Health Science Jamshoro and Hyderabad, using an array of methods and techniques, questionnaire, and serum samples. Data were collected for serum melatonin, PTSD score, and ISI (Insomnia severity index) score for 116 participants. Data were analysed by using SPSC 26.0 software. Results: A total of 116 participants, out of which 48 (41.3%) were male and 68 (58.6%) were female, The mean age was 36.65 years, and the mean BMI was 29.39. We found that strong negative correlation between serum Melatonin and PTSD (r value= -.907**) with (P=0.001), a negative correlation of serum melatonin with insomnia (-.585**) and we also found a relationship with all these variables which shows a strong dependency. We also found out the prevalence of PTSD (13.71%) and Insomnia (42.25%) with (P=0.0001) and their dependency on departmental variations and the effect of work schedule. Conclusion: This study concludes serum melatonin is linked directly to variables, and then it can be used as primary prevention and potential adjuvant therapy for stress & insomnia.

Published
2024-06-30
How to Cite
Dars, J., Memon, S. F., Shaikh, S. A., Buledi, A. W., Mengal, A., & Tagar, M. (2024). Melatonin Mystery Key to A Sleepless Stress: A Cross-Sectional Study among Emergency Doctors of LUMHS, Sindh, Pakistan: Effects of Melatonin on Doctors Working in Emergency Department. Annals of Punjab Medical College, 18(2), 81-84. https://doi.org/10.29054/apmc/2024.1534

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