Using Intranasal Corticosteroids and Oral Antihistamines to Treat Allergic Rhinitis: A Comparison of The Mean Total Nasal Symptom Score

  • Arshad Ullah Afridi Associate Professor, Department of ENT, Shalamar Medical & Dental College/Shalamar Hospital, Lahore Pakistan
  • Rabia Zaman Khan Assistant Professor, Department of ENT Unit I, Fatima Jinnah Medical University, Lahore Pakistan
  • Umair Wahab Assistant Professor, ENT Unit I, Fatima Jinnah Medical University / Sir Ganga Ram Hospital, Lahore Pakistan
  • Ali Nasir Senior Registrar, Department of ENT, Fatima Memorial Hospital, Lahore Pakistan
  • Zubair Ahmed Senior Registrar, Department of ENT, Sheikh Zayed Hospital, Lahore Pakistan
  • Sarwat Iqbal Assistant Professor, Department of Medicine, Shalamar Medical & Dental College/ Shalamar Hospital, Lahore Pakistan
Keywords: Allergic rhinitis, Management, Intranasal corticosteroids, Oral anti-histamine, Total nasal symptom score

Abstract

Background: Allergic rhinitis (AR) is a global public health issue. The disease is a leading cause of death and disabilities globally. Objective: To compare the mean total nasal symptom score using intranasal corticosteroids with oral anti-histamine in management of allergic rhinitis. Study Design: Randomized controlled trial. Settings: Department of ENT, Shalamar Medical and Dental College/ Shalamar Hospital, Lahore Pakistan. Duration: 1st January 2023 to 30 June 2023. Methods: 100 cases equally divided in two groups A&B, Intranasal corticosteroids were administered in Group A and oral anti-histamine in Group B cases, The final evaluation was done after 4 weeks of treatment. Results: Comparison of mean total nasal symptom score using intranasal corticosteroids with oral anti-histamine in management of allergic rhinitis shows that 1.51 ± 0.37 score in Group-A and 1.27 ± 0.11 score in Group-B, (p-value < 0.05). Conclusion: We found that the use of intranasal corticosteroids resulted in a substantially reduced mean total nasal symptom score compared to the use of oral anti-histamine in the treatment of allergic rhinitis.

Published
2023-09-30
How to Cite
Afridi, A. U., Khan, R. Z., Wahab, U., Nasir, A., Ahmed, Z., & Iqbal, S. (2023). Using Intranasal Corticosteroids and Oral Antihistamines to Treat Allergic Rhinitis: A Comparison of The Mean Total Nasal Symptom Score. Annals of Punjab Medical College, 17(3), 358-360. https://doi.org/10.29054/apmc/2023.1449