Abnormal Large Bowel Wall Thickness; As A Diagnostic Marker of Colorectal Carcinoma
Objective: To determine the abnormal large bowel thickness as marker of colorectal cancer among clinically suspected patients by using histopathology as gold standard. Study Design: Descriptive study. Settings: Radiology department of Bilawal Medical College Jamshoro Pakistan. Duration: November 2017 to October 2018. Methodology: Patients more than 16 years of the age referred for contrast enhanced CT (CECT) of abdomen due to clinical suspicion of colorectal carcinoma, having bleeding per rectum, altered bowel habit, anemia with hemoglobin <10gm/dl or positive fecal occult test, patients underwent histopathology after positive findings of contrast enhanced CT (CECT) and either of the gender were included. Patients having bowel wall thickness >3mm were considered as colorectal carcinoma and conformed after histopathological findings. All the data was recorded in the self-made proforma. Results: Total 150 patients were selected their mean age was 46.78 years and mean of wall thickness was 15.73 mm. Males were found in majority 61.3%. Colorectal carcinoma was significantly associated with elevated bowel wall thickness, p-value 0.008. There was no significant difference in colorectal carcinoma according to gender, p-value 0.815. Conclusion: Large bowel wall thickness >10mm on contrast enhanced CT (CECT) is the best indicator for early diagnosis of colorectal carcinoma.