Vitamin D Deficiency in the Patients of Diabetes Mellitus and Its Correlation with HbA1c
Background: Diabetes mellitus is a prevalent chronic metabolic disorder. Elevated HbA1c levels are associated with a higher risk of diabetes-related complications. Some studies have suggested a potential correlation between vitamin D levels and HbA1c, indicating that vitamin D deficiency may contribute to poor glycemic control. Objective: To evaluate the vitamin d deficiency in the patients of type-II diabetes mellitus and its correlation with HbA1c. Study Design: Cross-sectional study. Settings: Department of Medicine, PUMHS Nawabshah and MMC MirpurKhas Pakistan. Duration: 6 months of period from July 2021 to December 2021. Methods: Study included patients with type 2 diabetes mellitus, aged over 40 years and both genders. A 5ml blood sample was collected from each participant after obtaining informed consent and sent to the diagnostic laboratory to determine the HbA1c levels and vitamin D status. Data collection was carried out using a self-made study proforma, and the data were analyzed using SPSS version 26. Results: A total of 58 diabetes patients were evaluated for vitamin D deficient and its correlation with HbA1c. Overall mean age of the patients was 53.32 ± 8.54 years. Males were 28(48.3%) and females were 30(51.7%). Most of the patients 48.30% had moderately decreased vitamin D level, followed by 25.90% cases had mild deficiency, only one case had severely decreased vitamin D level. There was a significant negative correlation between vitamin d level and HbA1c (r= - 0.314) (p= 0.016). Conclusion: Among individuals with type 2 diabetes mellitus, there was a higher prevalence of vitamin D deficiency and insufficiency. Additionally, a significant inverse relationship was observed between vitamin D deficiency and HbA1c levels.